Article
MHC class I phenotype and function of human beta 2-microglobulin transgenic murine lymphocytes.
Scandinavian journal of immunology - 1 Dec 1996
Bjerager L, Pedersen L O, Bregenholt S, Nissen M H, Claesson M H
Abstract excerpt
Lymphoid cells from beta 2-microglobulin (beta 2m) knockout mice transgenic for human (h) beta 2m (C57BL/10 m beta 2m-/h beta 2m+) were compared with normal mice for their binding to exogenously added h beta 2m, binding to a H-2Db peptide and for functional activity in a one-way allogenic MLC. Based on data from cellular binding studies, Scatchard analyses and flow cytometry, it is concluded that exogenous h beta...
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