Article
MHC class I phenotype and function of human beta 2-microglobulin transgenic murine lymphocytes.
Scandinavian journal of immunology - 1 Dec 1996
Bjerager L, Pedersen L O, Bregenholt S, Nissen M H, Claesson M H
Abstract excerpt
Lymphoid cells from beta 2-microglobulin (beta 2m) knockout mice transgenic for human (h) beta 2m (C57BL/10 m beta 2m-/h beta 2m+) were compared with normal mice for their binding to exogenously added h beta 2m, binding to a H-2Db peptide and for functional activity in a one-way allogenic MLC. Ba...
Topics
- Animals
- Antigens, Viral
- Flow Cytometry
- H-2 Antigens
- Histocompatibility Antigen H-2D
- Histocompatibility Antigens Class I
- Humans
- Lymph Nodes
- Lymphocytes
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Transgenic
- Phenotype
- Respirovirus
- Spleen
- beta 2-Microglobulin