Article
Bioequivalence and absolute bioavailability of oblong and coated levomepromazine tablets in CYP2D6 phenotyped subjects.
International journal of clinical pharmacology and therapeutics - 1 Dec 1995
Bagli M, Höflich G, Rao M L, Langer M, Baumann P, Kolbinger M, Barlage U, Kasper S, Möller H J
Abstract excerpt
The bioequivalence and absolute bioavailability of oblong and coated levomepromazine tablets were studied in 12 healthy volunteers. A 1-hour intravenous infusion served as the reference. Serum concentrations of levomepromazine were quantified with a specific high-performance liquid chromatographic method and electrochemical detection. The 2 oral formulations were bioequivalent. After oral administration of oblong...
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