Article
Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval.
Oncogene - 5 Dec 1996
Rosenberg J E, Lisle D K, Burwick J A, Ueki K, von Deimling A, Mohrenweiser H W, Louis D N
Abstract excerpt
Allelic loss of chromsome 19q occurs frequently in malignant gliomas, suggesting the presence of a chromosome 19q glioma tumor suppressor gene. Deletion mapping studies have delineated a 3.5 Mb candidate region between D19S219 and HRC. Cloned sequences from the proximal 425 kb of this interval, however, have not shown tumor-specific alterations. To refine the location of the tumor suppressor gene further, we...
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