Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval.

Article

Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval.

Oncogene - 5 Dec 1996

Rosenberg J E, Lisle D K, Burwick J A, Ueki K, von Deimling A, Mohrenweiser H W, Louis D N

Abstract excerpt

Allelic loss of chromsome 19q occurs frequently in malignant gliomas, suggesting the presence of a chromosome 19q glioma tumor suppressor gene. Deletion mapping studies have delineated a 3.5 Mb candidate region between D19S219 and HRC. Cloned sequences from the proximal 425 kb of this interval, h...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 19
Gene Deletion
Genes, Tumor Suppressor
Genetic Markers
Glioma
Humans
Polymorphism, Genetic

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