Loci associated with malignant progression in astrocytomas: a candidate on chromosome 19q.

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Article

Loci associated with malignant progression in astrocytomas: a candidate on chromosome 19q.

Cancer research - 15 Mar 1994

von Deimling A, Bender B, Jahnke R, Waha A, Kraus J, Albrecht S, Wellenreuther R, Fassbender F, Nagel J, Menon A G

Abstract excerpt

WHO grades II and III astrocytomas frequently exhibit loss of genetic material on chromosomes 9p, 11p, 17p, 19q, and 22q, indicating that these chromosomal regions harbor tumor suppressor genes involved in the pathogenesis of astrocytic neoplasms. The present study was conducted to examine whethe...

Topics

Adult
Alleles
Astrocytoma
Brain Neoplasms
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 9
ErbB Receptors
Female
Gene Amplification
Gene Deletion
Genes, Tumor Suppressor
Genetic Variation
Humans
Interferon-alpha
Male

Source

Open in PubMed

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PMID: 8137236

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8137236-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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