Article
Disruption of the hslU gene, which encodes an ATPase subunit of the eukaryotic 26S proteasome homolog in Escherichia coli, suppresses the temperature-sensitive dnaA46 mutation.
Biochemical and biophysical research communications - 4 Dec 1996
Katayama T, Kubota T, Takata M, Akimitsu N, Sekimizu K
Abstract excerpt
The Escherichia coli hslVU genes encode subunits of an ATP-dependent protease, a homolog of the eukaryotic 26S proteasome. We found that the hslU gene is required for the temperature (40 degrees C)-sensitive phenotype of the dnaA46 mutant, while other soluble ATP-dependent proteases, La (Lon) and Ti (Clp), were unrelated to this dnaA46 phenotype. Disruption of the hslU gene inhibited cell growth at high...
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