Article
HSP27 locus cosegregates with left ventricular mass independently of blood pressure.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 1996
Hamet P, Kaiser M A, Sun Y, Pagé V, Vincent M, Kren V, Pravenec M, Kunes J, Tremblay J, Samani N J
Abstract excerpt
Left ventricular hypertrophy remains a significant clinical problem and a predictor of fatal outcome in hypertension. Blood pressure per se and environmental modifiers including stress affect cardiac mass. Heat shock proteins are involved in the stress response as well as in the regulation of cardiac growth and cytoprotection. The present study evaluates heat shock protein 27 as a locus marker or candidate gene...
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