Article
Genes of stress in experimental hypertension.
Clinical and experimental pharmacology & physiology - 1 Nov 1994
Hamet P, Sun Y L, Malo D, Kong D, Kren V, Pravenec M, Kunes J, Dumas P, Richard L, Gagnon F
Abstract excerpt
1. A significant portion of blood pressure variance is modified by the environment. 2. The present report summarizes evidence that: (i) the environmental response is genetically determined; (ii) various stressors can evoke a differential response in hypertensive animals and constitute its intermediate phenotypes; (iii) the response to heat stress can be assigned to a single 'thermosensitivity' locus; (iv)...
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