Article
Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine Ryr2 receptor as a candidate.
Circulation - 23 Jan 2001
Zhao L, Sebkhi A, Nunez D J, Long L, Haley C S, Szpirer J, Szpirer C, Williams A J, Wilkins M R
Abstract excerpt
BACKGROUND: Fischer 344 (F344) rats are relatively resistant to hypoxia-induced right ventricular (RV) hypertrophy compared with the Wistar-Kyoto (WKY) strain. These 2 strains were used to examine the genetic basis for the differential response. METHODS AND RESULTS: Male F(2) offspring from an F3...
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