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Article

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.

Genes & development - 1 Nov 1996

Sluss H K, Han Z, Barrett T, Goberdhan D C, Wilson C, Davis R J, Ip Y T

Abstract excerpt

The Drosophila MAP kinase DJNK is a homolog of the mammalian c-Jun amino-terminal kinase (JNK). Mutations in the DJNK gene correspond to the complementation group basket. DJNK is phosphorylated and activated by the Drosophila MAP kinase kinase HEP. Substrates of DJNK include the transcription factor DJun. DJNK participates in multiple physiological processes. Exposure to endotoxic lipopolysaccharide initiates an...

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PMID: 8946915
DOI: 10.1101/gad.10.21.2745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.PMID 8946915Read ↗

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