Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Fitness spectrum among random mutants on Mt. Fuji-type fitness landscape.

Journal of theoretical biology - 21 Oct 1996

Aita T, Husimi Y

Abstract excerpt

Statistical properties of a Mt. Fuji-type fitness landscape on a multi-valued sequence space were analysed. We constructed the model landscape based on additivity of the free energy contributed by each residue on a biopolymer, introducing "tolerance functions" that describe tolerance to residue s...

Topics

Join the communities discussing this publication.

Mutation
Protein Binding
Evolution, Molecular
Models, Statistical
Biopolymers

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8944894
DOI: 10.1006/jtbi.1996.0189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8944894-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fitness spectrum among random mutants on Mt. Fuji-type fitness landscape.PMID 8944894Read ↗

Surveying a local fitness landscape of a protein with epistatic sites for the study of directed evolution.Semantic proximity Read ↗

From amino acid landscape to protein landscape: analysis of genetic codes in terms of fitness landscape.Semantic proximity Read ↗

Predictability of evolutionary trajectories in fitness landscapes.Semantic proximity Read ↗

Thermodynamical interpretation of evolutionary dynamics on a fitness landscape in an evolution reactor, II.Semantic proximity Read ↗

Theory of evolutionary molecular engineering through simultaneous accumulation of advantageous mutations.Semantic proximity Read ↗

Experimental rugged fitness landscape in protein sequence space.Semantic proximity Read ↗

Local fitness landscape of the green fluorescent protein.Semantic proximity Read ↗

Landscapes: complex optimization problems and biopolymer structures.Semantic proximity Read ↗

Extracting characteristic properties of fitness landscape from in vitro molecular evolution: a case study on infectivity of fd phage to E.coli.Semantic proximity Read ↗

Statistical theory of protein sequence design by random mutation.Semantic proximity Read ↗

Evolution models with lethal mutations on symmetric or random fitness landscapes.Semantic proximity Read ↗

Designing a neural network for the constraint optimization of the fitness functions devised based on the load minimization of the genetic code.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.