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Article

Extracting characteristic properties of fitness landscape from in vitro molecular evolution: a case study on infectivity of fd phage to E.coli.

Journal of theoretical biology - 7 Jun 2007

Aita Takuyo, Hayashi Yuuki, Toyota Hitoshi, Husimi Yuzuru, Urabe Itaru, Yomo Tetsuya

Abstract excerpt

We have developed a methodology for extracting characteristic properties of a fitness landscape of interest by analyzing fitness data on an in vitro molecular evolution. The in vitro evolution is required to be conducted as the following "adaptive walk": a single parent sequence generates N mutant sequences as its offsprings, and the fittest individual among the N offsprings will become a new parent in the next...

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Identifiers

PMID: 17316695
DOI: 10.1016/j.jtbi.2006.12.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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