Article
Evolution models with lethal mutations on symmetric or random fitness landscapes.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Jul 2010
Kirakosyan Zara, Saakian David B, Hu Chin-Kun
Abstract excerpt
We calculate the mean fitness for evolution models, when the fitness is a function of the Hamming distance from a reference sequence, and there is a probability that this fitness is nullified (Eigen model case) or tends to the negative infinity (Crow-Kimura model case). We calculate the mean fitness of these models. The mean fitness is calculated also for the random fitnesses with logarithmic-normal distribution,...
Topics
- Animals
- Biological Evolution
- Genetics, Population
- Humans
- Models, Genetic
- Models, Statistical
- Mutation
- Survival Analysis
- Survival Rate