Article
The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry.
Clinical pharmacology and therapeutics - 1 Nov 1996
Chen S, Chou W H, Blouin R A, Mao Z, Humphries L L, Meek Q C, Neill J R, Martin W L, Hays L R, Wedlund P J
Abstract excerpt
OBJECTIVES: This study examined factors that affect cost, reliability, and the value of determining the cytochrome P450 2D6 (CYP2D6) polymorphism in clinical practice. STUDY DESIGN: The method of deoxyribonucleic acid isolation, sample preparation, oligonucleotide primers, and polymerase chain re...
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