Article
Endoderm-specific gene expression in embryonic stem cells differentiated to embryoid bodies.
Experimental cell research - 25 Nov 1996
Abe K, Niwa H, Iwase K, Takiguchi M, Mori M, Abé S I, Abe K, Yamamura K I
Abstract excerpt
Mouse embryonic stem cells can differentiate into various cell types within cell aggregates called embryoid bodies (EBs). This structure consists of ectodermal, mesodermal, and endodermal tissues, which resemble the embryo of egg-cylinder stage. After 8-10 days in culture, about half of the EBs expand into large cystic structures homologous to visceral yolk sac of postimplantation embryos. To study endoderm...
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