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Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions

16 Nov 2012

Abstract excerpt

Many cellular responses during development are regulated by interactions between integrin receptors and extracellular matrix proteins (ECMPs). Although the majority of recent studies in human embryonic stem cell (hESC) differentiation have focused on the role of growth factors, such as FGF, TGFβ, and WNT, relatively little is known about the role of ECMP-integrin signaling in this process. Moreover, current...

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PMID: 23154389
DOI: 10.1038/cdd.2012.138

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