Article
A bifunctional urease enhances survival of pathogenic Yersinia enterocolitica and Morganella morganii at low pH.
Journal of bacteriology - 1 Nov 1996
Young G M, Amid D, Miller V L
Abstract excerpt
To infect a susceptible host, the gastrointestinal pathogen Yersinia enterocolitica must survive passage through the acid environment of the stomach. In this study, we showed that Y. enterocolitica serotype O8 survives buffered acidic conditions as low as pH 1.5 for long periods of time provided urea is available. Acid tolerance required an unusual cytoplasmically located urease that was activated 780-fold by...
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