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Article

Contribution of urease to colonization by Shiga toxin-producing Escherichia coli.

Infection and immunity - 1 Aug 2012

Steyert Susan R, Kaper James B

Abstract excerpt

Shiga toxin-producing Escherichia coli (STEC) is a food-borne pathogen with a low infectious dose that colonizes the colon in humans and can cause severe clinical manifestations such as hemolytic-uremic syndrome. The urease enzyme, encoded in the STEC chromosome, has been demonstrated to act as a virulence factor in other bacterial pathogens. The NH(3) produced as urease hydrolyzes urea can aid in buffering...

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Identifiers

PMID: 22665380
DOI: 10.1128/IAI.00210-12
PMCID: PMC3434572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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