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Mutations in an Abf1p binding site in the promoter of yeast RPO26 shift the transcription start sites and reduce the level of RPO26 mRNA.

Yeast (Chichester, England) - 1 Oct 1996

Nouraini S, Hu J, McBroom L D, Friesen J D

Abstract excerpt

A binding site for the transcription factor Abf1p was identified as an important promoter element of the gene that encodes Rpo26, a subunit common to all three yeast nuclear RNA polymerases (RNAP). Mutations in the Abf1p binding site were identified among a pool of rpo26 mutant alleles that confer synthetic lethality in combination with a temperature-sensitive mutation (rpo21-4) in the gene that encodes the...

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Identifiers

PMID: 8923739
DOI: 10.1002/(SICI)1097-0061(199610)12:13%3C1339::AID-YEA31%3E3.0.CO;2-C

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