Article
[Mutations of hMSH2 gene and hMLH1 gene in human colovectal carcinomas].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1996
Yokozaki H, Yamamoto S, Tahara E
Abstract excerpt
Mutations of the hMSH2 and hMLH1 mismatch repair system genes in hereditary non-polyposis colorectal cancer (Lynch) syndrome as well as sporadic colorectal cancers with microsatellite instabilities are overviewed. Alterations of genes involved in DNA repair would be the cause of genetic instabili...
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