Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Mutation of the mismatch repair genes for carcinogenesis of sporadic colorectal cancers with RER-positive phenotype].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1996

Sasaki S, Nakamura Y

Abstract excerpt

Genetic instability, monitored by (a) replication error, is a feature of many hereditary and sporadic colorectal cancers. When such tumors are familial, the genetic instability is thought to be triggered by inherited mutations in DNA-mismatch repair genes but the mechanism by which sporadic tumors exhibit RER+ phenotypes is not as well understood. We examined RER in 129 sporadic colorectal tumors. In eight of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colonic Neoplasms
Share to DNA Repair
Share to DNA Replication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Phenotype

Source

Identifiers

PMID: 8920665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Mutation of the mismatch repair genes for carcinogenesis of sporadic colorectal cancers with RER-positive phenotype].PMID 8920665Read ↗

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.Semantic proximity Read ↗

Undectable expression of hMLH1 protein in sporadic colorectal cancer with replication error phenotype.Semantic proximity Read ↗

Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability.Semantic proximity Read ↗

Four new mutations in the DNA mismatch repair gene MLH1 in colorectal cancers with microsatellite instability. Mutations in brief no. 157. Online.Semantic proximity Read ↗

[Microsatellite instability--a new aspects in genetics and molecular biology of hereditary nonpolyposis and sporadic colorectal tumors].Semantic proximity Read ↗

DNA mismatch repair genes and colorectal cancerSemantic proximity Read ↗

[What's new about microsatellite instability significance in human carcinogenesis?].Semantic proximity Read ↗

Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas.Semantic proximity Read ↗

Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer.Semantic proximity Read ↗

Clinicopathologic and genetic features of nonfamilial colorectal carcinomas with DNA replication errors.Semantic proximity Read ↗

Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables.Semantic proximity Read ↗

Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.