Article
[What's new about microsatellite instability significance in human carcinogenesis?].
Bulletin du cancer - 1 Nov 1997
Vaurs C, Bignon Y J
Abstract excerpt
Microsatellite instabilities (MIN) represent a new type of mutation characterized by genomic instability (or replication error phenotype, RER+). First identified in sporadic and familial colorectal tumors, the RER+ phenotype has been sought in multiple types of cancers. Thus, two types of instabi...
Topics
- Cell Division
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA Damage
- DNA Repair
- Genetic Markers
- Humans
- Microsatellite Repeats
- Mutation
- Neoplasms
- Prognosis