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Article

20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway.

Nature - 21 Nov 1996

Yamashita Y M, Nakaseko Y, Samejima I, Kumada K, Yamada H, Michaelson D, Yanagida M

Abstract excerpt

The 20S cyclosome complex (also known as the anaphase-promoting complex) has ubiquitin ligase activity and is required for mitotic cyclin destruction and sister chromatid separation. The formation and activation of the 20S cyclosome complex is regulated by an unknown mechanism. Here we show that...

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Identifiers

PMID: 8918880
DOI: 10.1038/384276a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8918880-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway.PMID 8918880Read ↗

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