Article
Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis.
Current biology : CB - 21 May 1998
Kumada K, Nakamura T, Nagao K, Funabiki H, Nakagawa T, Yanagida M
Abstract excerpt
BACKGROUND: The Cut1 and Cut2 proteins of the fission yeast Schizosaccharomyces pombe form a complex and are required for the separation of sister chromatids during anaphase. Polyubiquitinated Cut2 degrades at the onset of anaphase and this degradation, like that of mitotic cyclin, is dependent o...
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