Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterization of a cisplatin-resistant strain of Schizosaccharomyces pombe.

Molecular pharmacology - 1 Nov 1996

Perego P, Jimenez G, Howell S B

Abstract excerpt

A cis-diamminedichloroplatinum [DDP (cisplatin)]-resistant population of Schizosaccharomyces pombe was developed through chronic exposure of the 972 h- strain to increasing concentrations of the drug. The resulting cells, designated wtr2, were 5.25-fold resistant to DDP, are resistance was retained by clone isolated from this population in the absence of drug for > or = 5 months. After backcrossing and isolation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cisplatin
Share to Drug Resistance, Microbial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haploidy

Share to Phenotype

Share to Schizosaccharomyces

Source

Identifiers

PMID: 8913338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterization of a cisplatin-resistant strain of Schizosaccharomyces pombe.PMID 8913338Read ↗

Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants.Semantic proximity Read ↗

Characterization of chromate-sensitive and -tolerant mutants of Schizosaccharomyces pombe.Semantic proximity Read ↗

Cisplatin sensitivity correlates with its ability to cause cell cycle arrest via a wee1 kinase-dependent pathway in Schizosaccharomyces pombe.Semantic proximity Read ↗

The cytotoxicity of anthramycin to mutants of Schizosaccharomyces pombe deficient in DNA damage responses.Semantic proximity Read ↗

Single step selection of cis-diamminedichloroplatinum(II) resistant mutants from a human ovarian carcinoma cell line.Semantic proximity Read ↗

Biosynthesis of phytochelatins in the fission yeast. Phytochelatin synthesis: a second role for the glutathione synthetase gene of Schizosaccharomyces pombe.Semantic proximity Read ↗

Caffeine-resistance in S. pombe: mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle.Semantic proximity Read ↗

Multiple mechanisms of resistance to cisplatin toxicity in an Escherichia coli K12 mutant.Semantic proximity Read ↗

Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe.Semantic proximity Read ↗

Effects of decreased specific glutathione reductase activity in a chromate-tolerant mutant of Schizosaccharomyces pombe.Semantic proximity Read ↗

Isolation and characterization of a dihydrofolate reductase gene mutation in methotrexate-resistant Drosophila cells.Semantic proximity Read ↗

The role of glutathione biosynthesis in heavy metal resistance in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.