Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormal Pattern of Platelet APP Isoforms in Alzheimer Disease and Down Syndrome

1 Nov 1996

Abstract excerpt

OBJECTIVE: To determine if changes in levels of amyloid precursor protein (APP) isoforms in periphery are associated with Alzheimer disease and Down syndrome. DESIGN: After subjects were grouped according to diagnosis, APP isoform levels in platelets were compared. SETTING: University medical center. SUBJECTS: Ten patients who fulfilled diagnostic criteria for probable Alzheimer disease, 22 healthy volunteers,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Inflammatory Biomarkers in Disease Prognosis
Share to Platelet Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8912490
DOI: 10.1001/archneur.1996.00550110114019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormal Pattern of Platelet APP Isoforms in Alzheimer Disease and Down SyndromePMID 8912490Read ↗

Clinical aspects and biomarkers of Alzheimer's disease in Down syndrome.Semantic proximity Read ↗

Altered amyloid protein processing in platelets of patients with Alzheimer disease.Semantic proximity Read ↗

Patterns and severity of vascular amyloid in Alzheimer's disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer's disease.Semantic proximity Read ↗

Decreased platelet APP isoform ratios in autosomal dominant Alzheimer's disease: baseline data from a DIAN cohort subset.Semantic proximity Read ↗

Regulation and Expression of the Alzheimer's β/A4 Amyloid Protein Precursor in Health, Disease, and Down's SyndromeaSemantic proximity Read ↗

Alzheimer's Disease in the Down Syndrome: An Overview of Genetics and Molecular AspectsSemantic proximity Read ↗

Down syndrome, Alzheimer disease, and cerebral amyloid angiopathy: The complex triangle of brain amyloidosisSemantic proximity Read ↗

Aging and Alzheimer's disease in Down syndrome: Clinical and pathological changesSemantic proximity Read ↗

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional studySemantic proximity Read ↗

Elevated plasma amyloid beta-peptide 1-42 and onset of dementia in adults with Down syndrome.Semantic proximity Read ↗

Beta-amyloid, oxidative stress and down syndrome.Semantic proximity Read ↗

Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.