Article
Molecular determinants of sexual differentiation.
World journal of urology - 1 Jan 1996
Wiener J S, Marcelli M, Lamb D J
Abstract excerpt
The processes of sexual differentiation have been greatly clarified by molecular biologic discoveries over the past five years. Gonadal differentiation into a testis or ovaries is controlled by a multitude of genes beginning with SRY which is believed to represent the testis determining factor. Other genes involved include SF-1, WT-1, DAX-1, and SOX9. The fully developed testis produces Mullerian inhibiting...
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