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An association between type 1 diabetes and the interleukin-1 receptor type 1 gene. The DiMe Study Group. Childhood Diabetes in Finland.

Human immunology - 1 Nov 1996

Metcalfe K A, Hitman G A, Pociot F, Bergholdt R, Tuomilehto-Wolf E, Tuomilehto J, Viswanathan M, Ramachandran A, Nerup J

Abstract excerpt

The polygenic susceptibility to type 1 diabetes is well established and recent studies have demonstrated linkage of a further locus on chromosome 2q to disease. We have studied a polymorphism of the interleukin-1 receptor type 1 gene (IL1R1) on chromosome 2q in type 1 diabetic and control subjects from Finland, the United Kingdom, South India: three populations in which the risk of disease varies from very high...

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PMID: 8911996
DOI: 10.1016/s0198-8859(96)00206-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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