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Article

A high frequency of defective vif genes in peripheral blood mononuclear cells from HIV type 1-infected individuals.

AIDS research and human retroviruses - 1 Nov 1996

Tominaga K, Kato S, Negishi M, Takano T

Abstract excerpt

We studied the heterogeneity and intactness of the vif gene in six HIV-1-infected individuals at various clinical stages. The proviral vif sequences in peripheral blood mononuclear cells were amplified by PCR, followed by cloning and sequencing of 45 vif clones. The intraindividual diversity of the vif genes ranged from 0.45 to 3.3% and was not correlated with disease stage. Although the vif gene has been shown...

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Identifiers

PMID: 8911580
DOI: 10.1089/aid.1996.12.1543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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