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Article

In vivo genetic variability of the HIV-1 vif gene.

Virology - 15 Aug 1994

Wieland U, Hartmann J, Suhr H, Salzberger B, Eggers H J, Kühn J E

Abstract excerpt

The human immunodeficiency virus type 1 (HIV-1) vif gene encodes a 23-kDa protein (viral infectivity factor) whose exact mechanism of action is not entirely clear. Vif is believed to be highly conserved among different HIV-1 strains. We have analyzed the proviral vif sequences of 61 peripheral blood mononuclear cell samples from HIV-1 positive patients by direct solid phase sequencing and temperature gradient gel...

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Identifiers

PMID: 8030283
DOI: 10.1006/viro.1994.1453

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