Article
Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas.
Molecular cancer - 4 Sept 2006
Ribeiro Franclim R, Henrique Rui, Hektoen Merete, Berg Marianne, Jerónimo Carmen, Teixeira Manuel R, Lothe Ragnhild A
Abstract excerpt
BACKGROUND: In order to gain new insights into the molecular mechanisms involved in prostate cancer, we performed array-based comparative genomic hybridization (aCGH) on a series of 46 primary prostate carcinomas using a 1 Mbp whole-genome coverage platform. As chromosomal comparative genomic hybridization (cCGH) data was available for these samples, we compared the sensitivity and overall concordance of the two...
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