Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isochromosome 8q formation is associated with 8p loss of heterozygosity in a prostate cancer cell line.

The Prostate - 15 Sept 1999

Virgin J B, Hurley P M, Nahhas F A, Bebchuk K G, Mohamed A N, Sakr W A, Bright R K, Cher M L

Abstract excerpt

BACKGROUND: In advanced prostate cancer, loss of chromosomal regions on 8p is frequently associated with gain of 8q. We studied the gross chromosomal abnormalities associated with 8p loss of heterozygosity (LOH) in the prostate tumor cell line 1542 CP3Tx. The cell line was previously established from a primary prostatic adenocarcinoma by immortalization with a recombinant retrovirus carrying the E6 and E7 genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Banding
Share to Chromosome Painting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 8

Share to DNA Probes

Share to Karyotyping

Share to Loss of Heterozygosity

Share to Prostatic Neoplasms

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 10440875
DOI: 10.1002/(sici)1097-0045(19990915)41:1<49::aid-pros7>3.0.co;2-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isochromosome 8q formation is associated with 8p loss of heterozygosity in a prostate cancer cell line.PMID 10440875Read ↗

Comparative genomic hybridization, allelic imbalance, and fluorescence in situ hybridization on chromosome 8 in prostate cancer.Semantic proximity Read ↗

Allelotyping analysis at chromosome 13q of high-grade prostatic intraepithelial neoplasia and clinically insignificant and significant prostate cancers.Semantic proximity Read ↗

Chromosome <i>8p</i> Deletions and <i>8q</i> Gains are Associated with Tumor Progression and Poor Prognosis in Prostate CancerSemantic proximity Read ↗

Loss of chromosome arm 8p loci in prostate cancer: mapping by quantitative allelic imbalance.Semantic proximity Read ↗

Differential chromosome allelic imbalance in the progression of human prostate cancer.Semantic proximity Read ↗

Genetic pathways and new progression markers for prostate cancer suggested by microsatellite allelotyping.Semantic proximity Read ↗

Loss of Heterozygosity Analysis and DNA Copy Number Measurement on 8p in Bladder Cancer Reveals Two Mechanisms of Allelic LossSemantic proximity Read ↗

Allelotyping analysis at chromosome arm 8p of high-grade prostatic intraepithelial neoplasia and incidental, latent, and clinical prostate cancers.Semantic proximity Read ↗

8p22 loss concurrent with 8c gain is associated with poor outcome in prostate cancer.Semantic proximity Read ↗

Review of allelic loss and gain in prostate cancer.Semantic proximity Read ↗

Large-Scale Allelotype of Pancreaticobiliary Carcinoma Provides Quantitative Estimates of Genome-Wide Allelic LossSemantic proximity Read ↗

Homozygous and frequent deletion of proximal 8p sequences in human prostate cancers: Identification of a potential tumor suppressor gene siteSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.