Article
Application of genetic screening information to the management of medullary thyroid carcinoma and multiple endocrine neoplasia type 2.
Endocrinology and metabolism clinics of North America - 1 Mar 1996
Wohllk N, Cote G J, Evans D B, Goepfert H, Ordonez N G, Gagel R F
Abstract excerpt
Application of RET proto-oncogene mutation analysis to the clinical management of MEN 2 and FMTC has simplified and enhanced the power of earlier used screening and treatment efforts for hereditary MTC. The approaches outlined herein are cost-effective, have improved diagnostic accuracy, and hold...
Topics
- Base Sequence
- Carcinoma, Medullary
- Genetic Testing
- Humans
- Molecular Sequence Data
- Multiple Endocrine Neoplasia Type 2a
- Mutation
- Pedigree
- Proto-Oncogene Mas
- Proto-Oncogenes
- Thyroid Neoplasms
