Article
Application of genetic screening information to the management of medullary thyroid carcinoma and multiple endocrine neoplasia type 2.
Endocrinology and metabolism clinics of North America - 1 Mar 1996
Wohllk N, Cote G J, Evans D B, Goepfert H, Ordonez N G, Gagel R F
Abstract excerpt
Application of RET proto-oncogene mutation analysis to the clinical management of MEN 2 and FMTC has simplified and enhanced the power of earlier used screening and treatment efforts for hereditary MTC. The approaches outlined herein are cost-effective, have improved diagnostic accuracy, and hold the promise of improved cure rates for this neoplasm. Further studies to elucidate the mechanism by which these...
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