Multiple endocrine neoplasia type II and familial medullary thyroid carcinoma. Impact of genetic screening on management.

doi:10.1007/978-1-4615-6355-6_20

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Article

Multiple endocrine neoplasia type II and familial medullary thyroid carcinoma. Impact of genetic screening on management.

Cancer treatment and research - 1 Jan 1997

Gagel R F

Abstract excerpt

The identification of ret protooncogene mutations in MEN-II and Hirschsprung disease has not only improved the clinical management of these genetic conditions but has also provided important information regarding mechanisms of transformation and neural crest development. An indication of how neur...

Topics

Carcinoma, Medullary
Genetic Testing
Humans
Multiple Endocrine Neoplasia Type 2a
Multiple Endocrine Neoplasia Type 2b
Mutation
Pheochromocytoma
Proto-Oncogenes
Thyroid Neoplasms

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