Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retroviral mutation rates and A-to-G hypermutations during different stages of retroviral replication.

Journal of virology - 1 Nov 1996

Kim T, Mudry R A, Rexrode C A, Pathak V K

Abstract excerpt

Retroviruses mutate at a high rate in vivo during viral replication. Mutations may occur during proviral transcription by RNA polymerase II, during minus-strand DNA synthesis (RNA template) by viral reverse transcriptase, or during plus-strand DNA synthesis (DNA template) by reverse transcriptase. To determine the contributions of different stages of replication to the retroviral mutation rates, we developed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Viral
Share to Base Sequence
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Multigene Family

Share to Mutation

Share to Tumor Cells, Cultured

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 8892879
DOI: 10.1128/JVI.70.11.7594-7602.1996
PMCID: PMC190828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retroviral mutation rates and A-to-G hypermutations during different stages of retroviral replication.PMID 8892879Read ↗

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations.Semantic proximity Read ↗

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions.Semantic proximity Read ↗

Determination of retroviral mutation rates using spleen necrosis virus-based vectors and helper cells.Semantic proximity Read ↗

Characterization of large deletions occurring during a single round of retrovirus vector replication: novel deletion mechanism involving errors in strand transfer.Semantic proximity Read ↗

Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation rate.Semantic proximity Read ↗

Use of single-cycle analysis to study rates and mechanisms of retroviral mutation.Semantic proximity Read ↗

High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector.Semantic proximity Read ↗

Rates of spontaneous mutation among RNA viruses.Semantic proximity Read ↗

Direct determination of the point mutation rate of a murine retrovirus.Semantic proximity Read ↗

Naturally Occurring Hepatitis B Virus Genomes Bearing the Hallmarks of Retroviral G → A HypermutationSemantic proximity Read ↗

The rate and character of spontaneous mutation in an RNA virus.Semantic proximity Read ↗

Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.