Article
Retroviral mutation rates and A-to-G hypermutations during different stages of retroviral replication.
Journal of virology - 1 Nov 1996
Kim T, Mudry R A, Rexrode C A, Pathak V K
Abstract excerpt
Retroviruses mutate at a high rate in vivo during viral replication. Mutations may occur during proviral transcription by RNA polymerase II, during minus-strand DNA synthesis (RNA template) by viral reverse transcriptase, or during plus-strand DNA synthesis (DNA template) by reverse transcriptase...
Topics
- Animals
- Base Sequence
- DNA, Viral
- Deoxyribonuclease BamHI
- Deoxyribonuclease HindIII
- Dogs
- Gammaretrovirus
- Gene Deletion
- Lac Operon
- Molecular Sequence Data
- Multigene Family
- Mutagenesis, Insertional
- Mutation
- Proviruses
- Tumor Cells, Cultured
- Virus Replication