Article
IL-4 differentiates naive CD8+ T cells to a "Th2-like" phenotype: a link between viral infections and bronchial asthma.
Annals of the New York Academy of Sciences - 31 Oct 1996
Coyle A J, Bertrand C, Tsuyuki S, Pircher H, Walti S, Le Gros G, Erard F
Abstract excerpt
Viral infections of the lung have been postulated to be a major factor in the etiology of bronchial asthma, a disease characterized by eosinophilic inflammation of the airways. In addition, upper respiratory tract infection in asthmatic individuals results in an exacerbation of the disease. Nevertheless, the mechanisms by which viral infection leads to disease exacerbation are poorly understood. CD8+ T cells play...
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