Article
Presence of a variant form of the estrogen receptor in peripheral blood mononuclear cells from normal individuals and lupus patients.
Journal of reproductive immunology - 1 Oct 1996
Wilson K B, Evans M, Abdou N I
Abstract excerpt
Estrogen may participate in the pathogenesis of systemic lupus erythematosus (SLE) via its intracellular receptor. To investigate the presence of various isoforms of the estrogen receptor (ER) in SLE we isolated RNA from mononuclear cells of lupus patients and normal controls. Using RT-PCR we were able to identify both the full length wild-type form and an isoform of the ER which precisely lacks exon V in both...
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