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Article

Estrogen receptor alpha gene polymorphism and systemic lupus erythematosus: a possible risk?

Lupus - 1 Jan 2005

Kassi E, Vlachoyiannopoulos P G, Kominakis A, Kiaris H, Moutsopoulos H M, Moutsatsou P

Abstract excerpt

Estrogens and their receptors may play a role in the pathogenesis of systemic lupus erythematosus. Genetic alterations in the exon 8-coding region of the estrogen receptor alpha alter the intracellular signalling of estrogens, leading in enhanced or diminished activity. We investigated whether genetic alterations in exon 8 of ERalpha gene are associated with the occurrence and clinical features of lupus disease....

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Share to DNA Mutational Analysis
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15934440
DOI: 10.1191/0961203305lu2104oa

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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