Article
Mismatch repair as a source of mutations in non-dividing cells.
Genetica - 1 Mar 1996
MacPhee D G
Abstract excerpt
This paper describes a mechanism which permits somatic cells to generate random mutations in the complete absence of cell proliferation. The mechanism itself is remarkably simple, involving a well-known cellular process (mismatch repair or MMR) which is primarily associated with mutation avoidance, but which is also capable of generating mutations when circumstances are not ideal for avoidance. When MMR operates...
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