Article
Cha4p of Saccharomyces cerevisiae activates transcription via serine/threonine response elements.
Genetics - 1 Oct 1996
Holmberg S, Schjerling P
Abstract excerpt
The CHA1 gene of Saccharomyces cerevisiae encodes the catabolic L-serine (L-threonine) deaminase responsible for the utilization of serine/threonine as nitrogen sources. Previously, we identified two serine/threonine response elements in the CHA1 promoter, UASCHA. We report isolation of a mutation, cha4-1, that impairs serine/threonine induction of CHA1 transcription. The cha4-1 allele causes noninducibility of a...
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