Article
Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans.
Experimental gerontology - 1 Nov 2001
Johnson T E, de Castro E, Hegi de Castro S, Cypser J, Henderson S, Tedesco P
Abstract excerpt
We review the status of the hypothesis that interventions that increase the resistance to stress offer the potential for effective life prolongation and increased health. The work focuses on research in the nematode worm Caenorhabditis elegans and describes both published and unpublished results consistent with this hypothesis. Correlation between stress resistance and longevity among many gerontogene mutants is...
Topics
- Aging
- Animals
- Caenorhabditis elegans
- Disease Susceptibility
- Longevity
- Mutation
- Stress, Physiological