Article
The search for the genetic basis of aging: the identification of gerontogenes in the nematode Caenorhabditis elegans.
Journal of the American Geriatrics Society - 1 Sept 1992
Johnson T E, Lithgow G J
Abstract excerpt
Study of C. elegans has provided much information for gerontologists. The influence of the genome on life span is clearly observable, and at least one gerontogene, age-1, has been defined. Data relating to important evolutionary questions has emerged and will continue to be used in testing current hypotheses. We are using an approach unbiased by theoretical constraints to delineate aging processes simultaneously...
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