The search for the genetic basis of aging: the identification of gerontogenes in the nematode Caenorhabditis elegans.

doi:10.1111/j.1532-5415.1992.tb01993.x

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Article

The search for the genetic basis of aging: the identification of gerontogenes in the nematode Caenorhabditis elegans.

Journal of the American Geriatrics Society - 1 Sept 1992

Johnson T E, Lithgow G J

Abstract excerpt

Study of C. elegans has provided much information for gerontologists. The influence of the genome on life span is clearly observable, and at least one gerontogene, age-1, has been defined. Data relating to important evolutionary questions has emerged and will continue to be used in testing curren...

Topics

Aging
Animals
Biomarkers
Caenorhabditis
Chromosome Mapping
Cloning, Molecular
Fertility
Genes
Genetic Markers
Genome
Genotype
Humans
Longevity
Models, Genetic
Polymorphism, Restriction Fragment Length

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