Article
High cerebrospinal tau levels are associated with the rs242557 tau gene variant and low cerebrospinal β-amyloid in Parkinson disease.
Neuroscience letters - 7 Jan 2011
Compta Yaroslau, Ezquerra Mario, Muñoz Esteban, Tolosa Eduardo, Valldeoriola Francesc, Rios Jose, Cámara Ana, Fernández Manel, Buongiorno Maria Teresa, Marti Maria Jose
Abstract excerpt
Cerebrospinal fluid (CSF) tau and phospho-tau levels have been associated with certain tau gene variants and low CSF amyloid-β (Aβ) levels in Alzheimer disease (AD), constituting potential biomarkers of molecular mechanisms underlying neurodegeneration. We aimed to assess whether such CSF-genetic endophenotypes are also present in Parkinson disease (PD). CSF tau, phospho-tau and Aβ levels were obtained from 38 PD...
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