Article
The type III protein translocation system of enteropathogenic Escherichia coli involves EspA-EspB protein interactions.
Molecular microbiology - 1 Mar 2000
Hartland E L, Daniell S J, Delahay R M, Neves B C, Wallis T, Shaw R K, Hale C, Knutton S, Frankel G
Abstract excerpt
Enteropathogenic Escherichia coli (EPEC), like many bacterial pathogens, use a type III secretion system to deliver effector proteins across the bacterial cell wall. In EPEC, four proteins, EspA, EspB, EspD and Tir are known to be exported by a type III secretion system and to be essential for 'attaching and effacing' (A/E) lesion formation, the hallmark of EPEC pathogenicity. EspA was recently shown to be a...
Topics
- Animals
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Biological Transport
- Cell Line
- Epithelial Cells
- Escherichia coli
- Escherichia coli Proteins
- Glutathione Transferase
- Humans