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Article

Esp-independent functional integration of the translocated intimin receptor (Tir) of enteropathogenic Escherichia coli (EPEC) into host cell membranes.

Cellular microbiology - 1 Apr 2006

Michgehl Silke, Heusipp Gerhard, Greune Lilo, Rüter Christian, Schmidt M Alexander

Abstract excerpt

The pathogenesis of enteropathogenic Escherichia coli (EPEC) is characterized by the type III secretion system-dependent exploitation of target cells that results in attaching and effacing (A/E) lesions, actin rearrangements and pedestal formation. This pathology is mediated by effector proteins which are translocated by the type III secretion system into the host cell such as the translocated intimin receptor...

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PMID: 16548888
DOI: 10.1111/j.1462-5822.2005.00655.x

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Esp-independent functional integration of the translocated intimin receptor (Tir) of enteropathogenic Escherichia coli (EPEC) into host cell membranes.PMID 16548888Read ↗

Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion.Semantic proximity Read ↗

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Intimate host attachment: enteropathogenic and enterohaemorrhagic<i>Escherichia coli</i>Semantic proximity Read ↗

Enterohaemorrhagic Escherichia coli Tir requires a C-terminal 12-residue peptide to initiate EspF-mediated actin assembly and harbours N-terminal sequences that influence pedestal length.Semantic proximity Read ↗

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Exploitation of host cells by enteropathogenic <i>Escherichia</i> <i>coli</i>Semantic proximity Read ↗

Two Enteropathogenic <i>Escherichia coli</i> Type III Secreted Proteins, EspA and EspB, Are Virulence FactorsSemantic proximity Read ↗

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