Article
Multivariate analysis of HLA loci in conjunction with a thyrotropin receptor codon 52 polymorphism in conferring risk of Graves' disease.
Thyroid : official journal of the American Thyroid Association - 1 Aug 1996
Cuddihy R M, Schaid D S, Bahn R S
Abstract excerpt
Recent reports have suggested that the HLA alleles DRB3*0101 or DQA1*0501 confer greater susceptibility to Graves' disease than does the DR3 allele. We have reported previously that a non-HLA-linked allele, a polymorphism in codon 52 of the human thyrotropin receptor gene, is highly associated with Graves' disease in females. To determine which of these four susceptibility alleles confers greater independent risk...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
