Article
Cytometry of cyclin proteins.
Cytometry - 1 Sept 1996
Darzynkiewicz Z, Gong J, Juan G, Ardelt B, Traganos F
Abstract excerpt
Cyclins are key components of the cell cycle progression machinery. They activate their partner cyclin-dependent kinases (CDKs) and possibly target them to respective substrate proteins within the cell. CDK-mediated phosphorylation of specific sets of proteins drives the cell through particular p...
Topics
- Animals
- Antineoplastic Agents
- Biomarkers, Tumor
- Cell Cycle
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinases
- Cyclins
- DNA, Neoplasm
- Flow Cytometry
- Gene Expression Regulation
- Humans
- Neoplasm Proteins
- Phenotype
- Proto-Oncogene Proteins
- Sensitivity and Specificity
- Tumor Cells, Cultured