Article
Cytometry of cyclin proteins.
Cytometry - 1 Sept 1996
Darzynkiewicz Z, Gong J, Juan G, Ardelt B, Traganos F
Abstract excerpt
Cyclins are key components of the cell cycle progression machinery. They activate their partner cyclin-dependent kinases (CDKs) and possibly target them to respective substrate proteins within the cell. CDK-mediated phosphorylation of specific sets of proteins drives the cell through particular phases or checkpoints of the cell cycle. During unperturbed growth of normal cells, the timing of expression of several...
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