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Article

Systematic characterization of cell cycle phase-dependent protein dynamics and pathway activities by high-content microscopy-assisted cell cycle phenotyping.

Genomics, proteomics & bioinformatics - 1 Dec 2014

Bruhn Christopher, Kroll Torsten, Wang Zhao-Qi

Abstract excerpt

Cell cycle progression is coordinated with metabolism, signaling and other complex cellular functions. The investigation of cellular processes in a cell cycle stage-dependent manner is often the subject of modern molecular and cell biological research. Cell cycle synchronization and immunostaining of cell cycle markers facilitate such analysis, but are limited in use due to unphysiological experimental stress,...

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Identifiers

PMID: 25458086
DOI: 10.1016/j.gpb.2014.10.004
PMCID: PMC4411490

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