Abnormalities in secondary cartilages in four lines of transgenic mice harboring two different types of mutations in the cartilage-specific type II collagen gene.

Abstract excerpt

A histological analysis was performed on two secondary cartilages, the mandibular condyle and the medial end of clavicle, in transgenic mice harboring two different types of mutations in the cartilage-specific type II collagen gene. Considerable differences were observed in the maturation zone of the chondrocytes and the hypertrophic cells of the growth regions of the two secondary cartilages examined between the...

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