Article
The role of TGF-ß1 in osteoarthritis of the temporomandibular joint in two genetic mouse models.
Archives of oral biology - 1 Jul 2016
Long E, Motwani R, Reece D, Pettit N, Hepworth J, Wong P, Reynolds P, Seegmiller R
Abstract excerpt
OBJECTIVE: The objective of this study is to elucidate osteoarthritis (OA) progression in the temporomandibular joint (TMJ) in two genetic mouse models by assessing the expression of an identified inflammatory marker associated with OA, viz., Tgf-ß1. This study provides mechanistic insight into disease progression based on the temporal expression of Tgf-ß1 in the TMJ. DESIGN: The two models included the...
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