Retarded skeletal development in transgenic mice with a type II collagen mutation.

Article

Retarded skeletal development in transgenic mice with a type II collagen mutation.

The American journal of pathology - 1 Dec 1996

Savontaus M, Metsranta M, Vuorio E

Abstract excerpt

Transgenic mice harboring specific mutations provide a tool for systematic studies on the effects of dominant mutations on embryonic development and growth. In the present study, several different techniques were employed to follow the development of growth abnormalities and other phenotypic cons...

Topics

Animals
Bone Development
Bone and Bones
Cartilage, Articular
Collagen
Embryonic and Fetal Development
In Situ Hybridization
Mice
Mice, Transgenic
Mutation
Osteochondrodysplasias

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