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Article

Retarded skeletal development in transgenic mice with a type II collagen mutation.

The American journal of pathology - 1 Dec 1996

Savontaus M, Metsranta M, Vuorio E

Abstract excerpt

Transgenic mice harboring specific mutations provide a tool for systematic studies on the effects of dominant mutations on embryonic development and growth. In the present study, several different techniques were employed to follow the development of growth abnormalities and other phenotypic consequences in the mouse litters from matings of heterozygous Del1 mice carrying six copies of a mouse type II collagen...

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Identifiers

PMID: 8952549
PMCID: PMC1865353

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Source receipt: pubmed, retrieved 7 Sept 2026.

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